Jefferson Manor Cape Girardeau, MO - Assisted Living Community size: Small (1-10) Get Prices & Availability (800) 341-4753 Office Jefferson Manor is a lovely assisted living community in Cape Girardeau, Missouri. It is within gorgeous Cape Girardeau County which is part of the Show Me State. + Read more Share this listing: Cape Girardeau Senior Services Near Me None Listed Cape Girardeau Senior Living Near Me